When tested in mice, psoriasis became more severe when more interferon kappa was present.
The finding will indicate how aggressively physicians should treat patients with the associated condition.
Inhibiting IRE1α, a molecule activated by the endoplasmic reticulum in neutrophils, counters disease progression in lupus mice.
Research finds juvenile myositis and lupus share an inflammatory pathway, but their pathophysiological differences may serve as diagnostic biomarkers in future studies.
A meta-analysis of lupus finds the disease is less common than previously thought, but disproportionally affects women and racial and ethnic minorities of both sexes.
National Research Effort Discovers Relationship Between Inflammation, Metabolism and Scleroderma Scarring
Study finds NAD+ break down leads to multi organ scarring, providing now a previously undiscovered pathogenic role of the enzyme CD38 in disease scarring.