The discovery could be a route to novel treatments for the autoimmune disease.

In patients with lupus, immune cells undergo an inflammatory transformation when migrating from the blood to the skin.

Inhibiting IRE1α, a molecule activated by the endoplasmic reticulum in neutrophils, counters disease progression in lupus mice.

Research finds juvenile myositis and lupus share an inflammatory pathway, but their  pathophysiological differences may serve as diagnostic biomarkers in future studies.

A meta-analysis of lupus finds the disease is less common than previously thought, but disproportionally affects women and racial and ethnic minorities of both sexes.

The main bioactive compound of ginger root lowers autoantibody production and helps halt disease progression in mice with antiphospholipid syndrome and lupus.