A new grant will allow Michigan Medicine researchers to explore personalized approaches to treating autoimmune diseases such as scleroderma, lupus, rheumatoid arthritis and others.

Researchers cause a lupus-like disease in mice by amplifying the amount of a single “master regulator” factor — suggesting both a root cause for known differences between the sexes and a target for new treatments.

U-M researchers are studying an overabundant signaling protein tied to UV light sensitivity in patients with lupus.

Researchers at the University of Michigan teamed up to investigate if kidney biomarkers would allow them to track lupus progression and signs of complications.