Inhibition of STAT3 signaling may improve survival in those with H3.3G34R/V mutant gliomas, animal studies suggest.
In cell and mouse models, metformin suppressed tumor growth in group A posterior fossa ependymomas.
A common mutation in gliomas sensitizes them to immunotherapy, a finding which researchers believe could have broader therapeutic implications for all glioma patients.
The device, which takes measurements every two minutes, was able to detect infection and cytokine release syndrome events several hours sooner than routine monitoring.
Pumping iron: inhibition of key pathway promotes iron-dependent cell death in pancreatic cancer cells
Cell culture study maps mechanisms underlying a new potential strategy for killing pancreatic cancer cells through a type of cell death known as ferroptosis.
A protein called PIKfyve impacts multiple processes involved in metabolism and cell death; blocking it is key to making immunotherapy work in prostate cancer.