Inhibition of STAT3 signaling may improve survival in those with H3.3G34R/V mutant gliomas, animal studies suggest.

In cell and mouse models, metformin suppressed tumor growth in group A posterior fossa ependymomas.

A common mutation in gliomas sensitizes them to immunotherapy, a finding which researchers believe could have broader therapeutic implications for all glioma patients.

A combination approach, which included metabolic reprogramming and immunotherapy, led to complete tumor regression in 60% of study mice.

Researchers have demonstrated that a new liquid biopsy approach overcomes traditional barriers to quickly and efficiently diagnose and monitor high-grade gliomas.

A roundup of several recent Michigan Medicine discoveries that are shedding new light on pediatric brain cancers and helping to improve treatment options.